Negative cofitness for GFF4686 from Variovorax sp. SCN45

Copper-sensing two-component system response regulator CusR
SEED: DNA-binding heavy metal response regulator
KEGG: two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR

Computing cofitness values with 61 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	GFF3074		Putative polysaccharide deacetylase	-0.56
2	GFF5291		Ferrichrome-iron receptor	-0.53
3	GFF234		Protein QmcA (possibly involved in integral membrane quality control)	-0.52
4	GFF3915		Ferrous iron transport periplasmic protein EfeO, contains peptidase-M75 domain and (frequently) cupredoxin-like domain	-0.51
5	GFF3758		NAD-specific glutamate dehydrogenase (EC 1.4.1.2); NADP-specific glutamate dehydrogenase (EC 1.4.1.4)	-0.51
6	GFF6156		Aerobic carbon monoxide dehydrogenase (quinone), medium chain (EC 1.2.5.3)	-0.51
7	GFF623		Demethylmenaquinone methyltransferase-like protein	-0.50
8	GFF2088		Putative lipase in cluster with Phosphatidate cytidylyltransferase	-0.50
9	GFF7290		Putative transmembrane protein	-0.47
10	GFF5090		Homoprotocatechuate degradative operon repressor	-0.46
11	GFF5329		SAM-dependent methyltransferase	-0.45
12	GFF259		Bis-ABC ATPase YheS	-0.45
13	GFF4256		Vanillate O-demethylase oxygenase subunit (EC 1.14.13.82)	-0.45
14	GFF6681		TonB-dependent siderophore receptor	-0.45
15	GFF7117		2-hydroxymuconic semialdehyde hydrolase (EC 3.7.1.9)	-0.45
16	GFF5586		Acetoin dehydrogenase E1 component beta-subunit (EC 2.3.1.190)	-0.44
17	GFF2504		Cell division protein ZapD	-0.44
18	GFF489		ATP-dependent Clp protease proteolytic subunit ClpP (EC 3.4.21.92)	-0.44
19	GFF5733		Methyl-accepting chemotaxis sensor/transducer protein	-0.44
20	GFF5580		Cyclopropane-fatty-acyl-phospholipid synthase (EC 2.1.1.79)	-0.43

Or look for positive cofitness