Negative cofitness for GFF4685 from Variovorax sp. SCN45

Copper sensory histidine kinase CusS
SEED: Heavy metal sensor histidine kinase
KEGG: two-component system, OmpR family, heavy metal sensor histidine kinase CusS

Computing cofitness values with 61 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	GFF4909		Two-component transcriptional response regulator, OmpR family	-0.49
2	GFF5149		Taurine ABC transporter, ATP-binding protein TauB	-0.48
3	GFF2287		ortholog of Bordetella pertussis (BX470248) BP3300	-0.47
4	GFF4319		Oxidoreductase, short-chain dehydrogenase/reductase family	-0.46
5	GFF3717		Putative aminoacrylate peracid reductase RutC @ RidA/YER057c/UK114 superfamily protein	-0.46
6	GFF3407		MaoC domain protein	-0.45
7	GFF2161		Dihydroorotase (EC 3.5.2.3)	-0.45
8	GFF4983		fumarate reductase/succinate dehydrogenase flavoprotein-like	-0.45
9	GFF2698		Transcriptional regulator, LysR family	-0.45
10	GFF1768		FIG00729359: hypothetical protein	-0.44
11	GFF6011		putative decarboxylase	-0.44
12	GFF6638		no description	-0.43
13	GFF6448		Glucans biosynthesis protein D precursor	-0.42
14	GFF2427		Transcriptional regulator, MarR family	-0.42
15	GFF5212		Alkaline phosphatase (EC 3.1.3.1)	-0.42
16	GFF5645		ABC transporter, permease protein (cluster 12, methionine/phosphonates) / ABC transporter, permease protein (cluster 12, methionine/phosphonates)	-0.42
17	GFF1430		hypothetical protein	-0.41
18	GFF1577		hypothetical protein	-0.41
19	GFF5057		Peptidoglycan D,D-transpeptidase MrdA (EC 3.4.16.4)	-0.41
20	GFF3578		Glutathione S-transferase, unnamed subgroup (EC 2.5.1.18)	-0.40

Or look for positive cofitness