Negative cofitness for GFF4621 from Variovorax sp. SCN45

Hydroxycarboxylate dehydrogenase (NADP+) HcxB
SEED: Malate dehydrogenase (EC 1.1.1.37)
KEGG: uncharacterized oxidoreductase

Computing cofitness values with 61 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 GFF2263 putative membrane protein -0.48
2 GFF5836 no description -0.46
3 GFF3740 Transcriptional regulator, MerR family -0.45
4 GFF3531 hypothetical protein -0.45
5 GFF5608 Quino(hemo)protein alcohol dehydrogenase, PQQ-dependent (EC 1.1.2.8) -0.44
6 GFF6217 hypothetical protein -0.43
7 GFF6533 Methylphosphotriester-DNA--protein-cysteine S-methyltransferase (EC 2.1.1.n11) / DNA-3-methyladenine glycosylase II (EC 3.2.2.21) -0.43
8 GFF4029 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) -0.42
9 GFF2078 hypothetical protein -0.42
10 GFF5044 ABC transporter, ATP-binding protein (cluster 9, phospholipid) -0.41
11 GFF3158 Sulfite dehydrogenase (quinone), iron-sulfur subunit SoeB (EC 1.8.5.6) -0.41
12 GFF6957 Coproporphyrinogen III oxidase, oxygen-independent (EC 1.3.99.22) -0.40
13 GFF6104 Glutamate/aspartate ABC transporter, substrate-binding protein GltI (TC 3.A.1.3.4) -0.40
14 GFF4582 TRAP-type C4-dicarboxylate transport system, small permease component -0.40
15 GFF2683 Protein containing domains DUF404, DUF407 -0.39
16 GFF6939 ABC-type antimicrobial peptide transport system, permease component -0.38
17 GFF5211 Alkaline phosphatase (EC 3.1.3.1) -0.38
18 GFF505 no description -0.38
19 GFF6771 2-dehydro-3-deoxygalactonokinase (EC 2.7.1.58) -0.38
20 GFF2369 putative 2-pyrone-4,6-dicarboxylic acid hydrolase -0.38

Or look for positive cofitness