Negative cofitness for GFF4537 from Variovorax sp. SCN45

Tetrapartite efflux system, inner membrane component FusBC-like
SEED: Inner membrane component of tripartite multidrug resistance system

Computing cofitness values with 61 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 GFF5663 ABC transporter, fused permease protein -0.58
2 GFF1207 no description -0.57
3 GFF1131 putative fatty acid desaturase -0.55
4 GFF3348 Putative lipase -0.53
5 GFF5532 Putative oxidoreductase -0.52
6 GFF1132 3-oxoacyl-[acyl-carrier-protein] synthase III (EC 2.3.1.41) -0.52
7 GFF6112 Oligopeptide ABC transporter, ATP-binding protein OppD (TC 3.A.1.5.1) -0.51
8 GFF5656 Formate dehydrogenase O gamma subunit (EC 1.2.1.2) -0.50
9 GFF534 Two-component system sensor histidine kinase -0.49
10 GFF3490 Putative amidase R03093 -0.49
11 GFF861 S-adenosylhomocysteine deaminase (EC 3.5.4.28); Methylthioadenosine deaminase -0.48
12 GFF4459 Acyl-CoA:1-acyl-sn-glycerol-3-phosphate acyltransferase (EC 2.3.1.51) -0.48
13 GFF2439 no description -0.48
14 GFF1640 Polyketide synthase modules and related proteins -0.47
15 GFF6330 BUG/TctC family periplasmic protein -0.47
16 GFF3666 Inner membrane protein YbiR, putative anion permease -0.46
17 GFF1706 ABC transporter, permease protein (cluster 10, nitrate/sulfonate/bicarbonate) / ABC transporter, permease protein (cluster 10, nitrate/sulfonate/bicarbonate) -0.45
18 GFF4098 hypothetical protein -0.45
19 GFF5687 FIG01027591: hypothetical protein -0.45
20 GFF4890 hypothetical protein -0.45

Or look for positive cofitness