Negative cofitness for GFF4535 from Variovorax sp. SCN45

Tetrapartite efflux system, membrane fusion component FusE-like
SEED: Membrane fusion component of tripartite multidrug resistance system

Computing cofitness values with 61 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 GFF1466 Quinone oxidoreductase (EC 1.6.5.5) -0.51
2 GFF1998 Two-component system sensor histidine kinase -0.47
3 GFF2502 O-antigen acetylase -0.46
4 GFF5091 5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase (EC 4.1.1.68) -0.45
5 GFF6061 3',5'-cyclic-nucleotide phosphodiesterase (EC 3.1.4.17) -0.45
6 GFF3789 hypothetical protein -0.45
7 GFF2474 Two-component transcriptional response regulator SMc02366, LuxR family -0.45
8 GFF3319 Fatty acid hydroxylase family (carotene hydroxylase/sterol desaturase) -0.44
9 GFF2541 FIG00899427: hypothetical protein -0.44
10 GFF5276 D-arabinitol 4-dehydrogenase (EC 1.1.1.11) -0.43
11 GFF6834 no description -0.43
12 GFF2010 Methylglutaconyl-CoA hydratase (EC 4.2.1.18) -0.43
13 GFF5524 Predicted transcriptional regulator -0.43
14 GFF1747 FIG00799528: hypothetical protein -0.42
15 GFF5794 Polyphosphate kinase 2 (EC 2.7.4.1) -0.42
16 GFF1343 macromolecule metabolism; macromolecule degradation; degradation of proteins, peptides, glycopeptides -0.42
17 GFF1921 ABC transporter, substrate-binding protein (cluster 10, nitrate/sulfonate/bicarbonate) -0.42
18 GFF5086 Glycine betaine transporter OpuD -0.42
19 GFF363 Transcriptional regulator, Crp/Fnr family -0.42
20 GFF800 hypothetical protein -0.42

Or look for positive cofitness