Negative cofitness for GFF4533 from Sphingobium sp. HT1-2

Na+-driven multidrug efflux pump
SEED: Multidrug and toxin extrusion (MATE) family efflux pump YdhE/NorM, homolog

Computing cofitness values with 18 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 GFF5140 Phytochrome, two-component sensor histidine kinase (EC 2.7.3.-) -0.77
2 GFF4242 FIG00877732: hypothetical protein -0.74
3 GFF1627 Tryptophan synthase alpha chain (EC 4.2.1.20) -0.70
4 GFF2410 Bacterioferritin (EC 1.16.3.1) -0.69
5 GFF216 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13), N-terminal domain -0.67
6 GFF878 Aerobic cobaltochelatase CobN subunit (EC 6.6.1.2) -0.67
7 GFF5233 Ribosome-associated ATPase RbbA -0.67
8 GFF4508 hypothetical protein -0.67
9 GFF718 hypothetical protein -0.67
10 GFF500 ATP:Cob(I)alamin adenosyltransferase (EC 2.5.1.17) -0.66
11 GFF705 Proline iminopeptidase (EC 3.4.11.5) -0.66
12 GFF877 Cob(I)alamin adenosyltransferase (EC 2.5.1.17) @ Cob(I)alamin adenosyltransferase (EC 2.5.1.17), clustered with cobalamin synthesis -0.66
13 GFF3082 hypothetical protein -0.64
14 GFF2370 Anthranilate synthase, aminase component (EC 4.1.3.27) -0.64
15 GFF826 Cobalamin synthase (EC 2.7.8.26) -0.64
16 GFF4345 UspA -0.63
17 GFF4892 protein tyrosine/serine phosphatase -0.63
18 GFF3686 Transcriptional regulator, LysR family -0.63
19 GFF3277 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) -0.63
20 GFF3985 hypothetical protein -0.63

Or look for positive cofitness