Negative cofitness for GFF4530 from Variovorax sp. SCN45

MBL-fold metallo-hydrolase superfamily
SEED: Metallo-beta-lactamase family protein

Computing cofitness values with 61 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 GFF6017 NADPH-dependent 7-cyano-7-deazaguanine reductase (EC 1.7.1.13) -0.86
2 GFF1861 Transcriptional regulator, IclR family -0.86
3 GFF2576 6-carboxy-5,6,7,8-tetrahydropterin synthase (EC 4.1.2.50) -0.86
4 GFF7306 FolM Alternative dihydrofolate reductase 1 -0.84
5 GFF341 ATP-dependent Clp protease ATP-binding subunit ClpA -0.83
6 GFF5483 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits -0.74
7 GFF2856 Transcriptional regulator, LysR family -0.73
8 GFF232 Arginine decarboxylase (EC 4.1.1.19); Ornithine decarboxylase (EC 4.1.1.17); Lysine decarboxylase (EC 4.1.1.18) -0.73
9 GFF3507 Transcriptional regulator, DeoR family -0.73
10 GFF6884 FIG00932717: hypothetical protein -0.73
11 GFF5214 7-cyano-7-deazaguanine synthase (EC 6.3.4.20) -0.72
12 GFF5383 DNA topoisomerase III, Burkholderia type (EC 5.99.1.2) -0.71
13 GFF6190 3-hydroxyisobutyrate dehydrogenase family protein -0.71
14 GFF2583 putative lipoprotein -0.71
15 GFF4383 hypothetical protein -0.70
16 GFF237 ABC-type branched-chain amino acid transport systems, periplasmic component -0.66
17 GFF5464 Transcriptional regulator, AcrR family -0.66
18 GFF2320 16S rRNA (guanine(966)-N(2))-methyltransferase (EC 2.1.1.171) -0.66
19 GFF2455 Transcriptional regulator RutR of pyrimidine catabolism (TetR family) -0.66
20 GFF1165 2-isopropylmalate synthase (EC 2.3.3.13) -0.66

Or look for positive cofitness