Negative cofitness for GFF4389 from Variovorax sp. SCN45

Type IV secretory pathway, VirD2 components (relaxase)
SEED: Type IV secretory pathway, VirD2 components (relaxase)

Computing cofitness values with 61 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 GFF2517 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase -0.60
2 GFF3413 Thioredoxin reductase (EC 1.8.1.9) -0.57
3 GFF2523 Peptide chain release factor N(5)-glutamine methyltransferase (EC 2.1.1.297) -0.56
4 GFF992 23S rRNA (adenine(2503)-C(2))-methyltransferase @ tRNA (adenine(37)-C(2))-methyltransferase (EC 2.1.1.192) -0.55
5 GFF1377 Phosphohydrolase (MutT/nudix family protein) -0.55
6 GFF2713 Beta-lactamase class C-like and penicillin binding proteins (PBPs) superfamily -0.55
7 GFF1713 no description -0.54
8 GFF5143 no description -0.54
9 GFF2006 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) -0.54
10 GFF3975 Metal-dependent hydrolase -0.54
11 GFF700 ABC transporter, permease protein 2 (cluster 4, leucine/isoleucine/valine/benzoate) / ABC transporter, ATP-binding protein 1 (cluster 4, leucine/isoleucine/valine/benzoate) -0.54
12 GFF2013 Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4) -0.54
13 GFF2400 no description -0.53
14 GFF2008 Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4) -0.53
15 GFF6198 D-malate dehydrogenase [decarboxylating] (EC 1.1.1.83) -0.53
16 GFF5071 AmpG permease -0.53
17 GFF3960 3'-to-5' oligoribonuclease (orn) -0.53
18 GFF582 Two-component system sensor histidine kinase -0.52
19 GFF4825 SWIB/MDM2 domain-containing proteins -0.52
20 GFF488 ATP-dependent Clp protease ATP-binding subunit ClpX -0.52

Or look for positive cofitness