Negative cofitness for GFF4365 from Variovorax sp. SCN45

3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
SEED: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
KEGG: 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit

Computing cofitness values with 61 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	GFF5373		Xylose isomerase-like TIM-barrel protein KPN_00539	-0.53
2	GFF4319		Oxidoreductase, short-chain dehydrogenase/reductase family	-0.53
3	GFF1956		Ser/Thr protein phosphatase family protein	-0.52
4	GFF2330		FOG: TPR repeat	-0.52
5	GFF7050		Enoyl-CoA hydratase (EC 4.2.1.17)	-0.52
6	GFF2698		Transcriptional regulator, LysR family	-0.51
7	GFF4300		Hydroxymethylglutaryl-CoA synthase (EC 2.3.3.10) / conserved protein associated with acetyl-CoA C-acyltransferase	-0.51
8	GFF1407		hypothetical protein	-0.51
9	GFF2079		BUG/TctC family periplasmic protein	-0.50
10	GFF2697		Oxidoreductase, short-chain dehydrogenase/reductase family	-0.50
11	GFF4921		hypothetical protein	-0.49
12	GFF2629		hypothetical protein	-0.49
13	GFF6223		T6SS outer membrane component TssL (ImpK/VasF) / OmpA/MotB domain	-0.48
14	GFF1415		Lactoylglutathione lyase and related lyases	-0.48
15	GFF6452		Putative diheme cytochrome c-553	-0.47
16	GFF5462		Cytosine deaminase (EC 3.5.4.1)	-0.47
17	GFF574		Tol-Pal system-associated acyl-CoA thioesterase	-0.46
18	GFF7210		Hydroxymethylpyrimidine ABC transporter, transmembrane component	-0.45
19	GFF4125		DNA-binding transcriptional regulator, MocR family / aminotransferase domain	-0.45
20	GFF4275		2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-0.45

Or look for positive cofitness