Negative cofitness for GFF4325 from Hydrogenophaga sp. GW460-11-11-14-LB1

Outer membrane component of tripartite multidrug resistance system

Computing cofitness values with 51 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	GFF5363		Drug resistance transporter, Bcr/CflA family	-0.47
2	GFF3759		PlcB, ORFX, ORFP, ORFB, ORFA, ldh gene	-0.42
3	GFF504		Branched-chain amino acid ABC transporter, amino acid-binding protein (TC 3.A.1.4.1)	-0.41
4	GFF5517		3-methylmercaptopropionyl-CoA dehydrogenase (DmdC)	-0.41
5	GFF290		RidA/YER057c/UK114 superfamily, group 2, YoaB-like protein	-0.41
6	GFF1743		hypothetical protein	-0.40
7	GFF5533		Membrane-bound lytic murein transglycosylase B precursor (EC 3.2.1.-)	-0.39
8	GFF3588		Imidazolonepropionase (EC 3.5.2.7)	-0.39
9	GFF877		Butyryl-CoA dehydrogenase (EC 1.3.99.2)	-0.38
10	GFF1043		Cytochrome oxidase biogenesis protein Sco1/SenC/PrrC, putative copper metallochaperone	-0.38
11	GFF394		transcriptional regulator, LuxR family	-0.38
12	GFF482		Enoyl-CoA hydratase (EC 4.2.1.17)	-0.37
13	GFF5683		Aquaporin Z	-0.37
14	GFF5776		putative transcriptional regulator, LysR family	-0.37
15	GFF134		Permease of the drug/metabolite transporter (DMT) superfamily	-0.37
16	GFF3687		NADH-ubiquinone oxidoreductase chain G (EC 1.6.5.3)	-0.36
17	GFF2296		Transcriptional regulator, IclR family	-0.36
18	GFF111		ATP-dependent DNA ligase (EC 6.5.1.1) clustered with Ku protein, LigD	-0.36
19	GFF815		FIG015547: peptidase, M16 family	-0.36
20	GFF5621		3-ketoacyl-CoA thiolase (EC 2.3.1.16) @ Acetyl-CoA acetyltransferase (EC 2.3.1.9)	-0.36

Or look for positive cofitness