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  • Negative cofitness for GFF4300 from Variovorax sp. SCN45

    Hydroxymethylglutaryl-CoA synthase (EC 2.3.3.10) / conserved protein associated with acetyl-CoA C-acyltransferase
    SEED: Hydroxymethylglutaryl-CoA synthase (EC 2.3.3.10)

    Computing cofitness values with 61 experiments...

    Genes with the strongest negative cofitness:

    Rank Hit Name Description Cofit  
    1 GFF635 Urea ABC transporter, permease protein UrtB -0.57
    2 GFF5853 Type I secretion system ATPase, LssB family LapB -0.57
    3 GFF7386 no description -0.55
    4 GFF5163 Soluble lytic murein transglycosylase (EC 4.2.2.n1) -0.55
    5 GFF801 Murein hydrolase activator NlpD -0.54
    6 GFF5314 Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ -0.53
    7 GFF4230 Transcriptional regulator of pyridoxine metabolism / Pyridoxamine phosphate aminotransferase (EC 2.6.1.54) -0.53
    8 GFF5643 no description -0.52
    9 GFF4365 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) -0.51
    10 GFF6803 N-acyl homoserine lactone hydrolase -0.51
    11 GFF1037 putative membrane protein -0.50
    12 GFF6549 no description -0.50
    13 GFF4237 no description -0.49
    14 GFF5476 ABC transporter, permease protein (cluster 3, basic aa/glutamine/opines) -0.49
    15 GFF4196 no description -0.48
    16 GFF5422 putative membrane protein -0.47
    17 GFF2492 BUG/TctC family periplasmic protein -0.47
    18 GFF3085 no description -0.47
    19 GFF5496 BUG/TctC family periplasmic protein -0.47
    20 GFF6794 hypothetical protein -0.46

    Or look for positive cofitness