Negative cofitness for GFF4227 from Variovorax sp. SCN45

Thiamine pyrophosphate-requiring enzymes
SEED: Acetolactate synthase large subunit (EC 2.2.1.6)

Computing cofitness values with 61 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	GFF5409		FIG00576366: hypothetical protein	-0.71
2	GFF6424		Phosphoenolpyruvate carboxykinase [GTP] (EC 4.1.1.32)	-0.67
3	GFF2683		Protein containing domains DUF404, DUF407	-0.67
4	GFF809		Acetyl-CoA acetyltransferase (EC 2.3.1.9)	-0.66
5	GFF1351		Acyl-CoA dehydrogenase	-0.64
6	GFF7374		FIG00984748: hypothetical protein	-0.63
7	GFF2682		Protein containing domains DUF403	-0.63
8	GFF6635		FIG00441227: hypothetical protein	-0.63
9	GFF5770		Flagellar biosynthesis protein FlhB	-0.62
10	GFF7372		Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B (EC 2.8.3.5)	-0.60
11	GFF5410		Adenylate cyclase (EC 4.6.1.1)	-0.60
12	GFF3386		hypothetical protein	-0.60
13	GFF5487		Thymidine phosphorylase (EC 2.4.2.4)	-0.60
14	GFF3582		Tripartite tricarboxylate transporter TctC family	-0.59
15	GFF6405		ABC transporter, substrate-binding protein (cluster 3, basic aa/glutamine/opines)	-0.59
16	GFF3730		Integral membrane protein	-0.59
17	GFF1656		hypothetical protein	-0.59
18	GFF770		Limit dextrin alpha-1,6-maltotetraose-hydrolase (EC 3.2.1.196)	-0.59
19	GFF1268		FIG022199: FAD-binding protein	-0.58
20	GFF338		Chloramphenicol acetyltransferase (EC 2.3.1.28)	-0.58

Or look for positive cofitness