Negative cofitness for GFF4192 from Sphingobium sp. HT1-2

NADP-dependent malic enzyme (EC 1.1.1.40)
SEED: NADP-dependent malic enzyme (EC 1.1.1.40)
KEGG: malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+)

Computing cofitness values with 18 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 GFF2594 Efflux ABC transporter, permease/ATP-binding protein -0.93
2 GFF2595 hypothetical protein -0.92
3 GFF2286 ATP-dependent Clp protease ATP-binding subunit ClpA -0.89
4 GFF785 Ammonium transporter -0.88
5 GFF2791 Two-component system sensor histidine kinase -0.88
6 GFF1149 Nitrogen regulation protein NtrB (EC 2.7.13.3) -0.88
7 GFF1660 NADP-dependent malic enzyme (EC 1.1.1.40) -0.87
8 GFF4046 anti-FecI sigma factor FecR -0.87
9 GFF1148 Nitrogen regulation protein NR(I), GlnG (=NtrC) -0.87
10 GFF2254 DksA family protein PA5536 (no Zn-finger) -0.86
11 GFF776 RNA polymerase sigma-54 factor RpoN -0.86
12 GFF3483 D-2-hydroxyglutarate dehydrogenase (EC 1.1.99.2) -0.85
13 GFF1764 Outer membrane protein A precursor -0.85
14 GFF1714 putative membrane protein -0.85
15 GFF2007 Phosphoenolpyruvate-protein phosphotransferase, nitrogen regulation associated -0.85
16 GFF4047 RNA polymerase ECF-type sigma factor -0.85
17 GFF2766 Cytochrome c precursor -0.84
18 GFF1715 hypothetical protein -0.84
19 GFF1746 Efflux ABC transporter for glutathione/L-cysteine, essential for assembly of bd-type respiratory oxidases => CydD subunit -0.83
20 GFF1150 tRNA-dihydrouridine synthase DusB -0.82

Or look for positive cofitness