Negative cofitness for GFF4178 from Variovorax sp. SCN45

5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
SEED: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
KEGG: methylenetetrahydrofolate reductase (NADPH)

Computing cofitness values with 61 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 GFF5235 General secretion pathway protein D / Type II secretion outermembrane pore forming protein (PulD) -0.63
2 GFF7262 no description -0.59
3 GFF6230 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain -0.58
4 GFF5402 Transcriptional regulator, IclR family -0.57
5 GFF2208 Type II/IV secretion system ATP hydrolase TadA/VirB11/CpaF, TadA subfamily -0.57
6 GFF7085 BUG/TctC family periplasmic protein -0.56
7 GFF5270 BUG/TctC family periplasmic protein -0.55
8 GFF4691 Cobalt/zinc/cadmium resistance protein CzcD -0.54
9 GFF2201 hypothetical protein -0.53
10 GFF335 Cytosine deaminase (EC 3.5.4.1) -0.52
11 GFF1037 putative membrane protein -0.52
12 GFF1055 Fumarylacetoacetate hydrolase family protein -0.51
13 GFF5635 Molybdenum ABC transporter permease protein ModB -0.51
14 GFF1355 Transcriptional regulator, LysR family -0.51
15 GFF660 FIG00974024: hypothetical protein -0.50
16 GFF2957 UPF0192 protein YfaS -0.50
17 GFF2182 Inner membrane component of TAM transport system -0.49
18 GFF2317 FIG015287: Zinc protease -0.49
19 GFF1960 Phenylalanine-4-hydroxylase (EC 1.14.16.1) -0.49
20 GFF3029 T6SS component TssM (IcmF/VasK) -0.49

Or look for positive cofitness