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  • Negative cofitness for GFF4143 from Variovorax sp. SCN45

    Dihydrofolate reductase (EC 1.5.1.3)
    SEED: Dihydrofolate reductase (EC 1.5.1.3)

    Computing cofitness values with 61 experiments...

    Genes with the strongest negative cofitness:

    Rank Hit Name Description Cofit  
    1 GFF7269 Altronate dehydratase (EC 4.2.1.7) -0.62
    2 GFF5954 Beta-lactamase class C-like and penicillin binding proteins (PBPs) superfamily -0.50
    3 GFF765 hypothetical protein -0.49
    4 GFF1274 Glutamate racemase (EC 5.1.1.3) -0.48
    5 GFF2248 Transcriptional regulatory protein RtcR -0.48
    6 GFF4787 ADP-ribosylglycohydrolase family protein -0.47
    7 GFF3149 RND efflux system, inner membrane transporter -0.47
    8 GFF1527 Ferrichrome-iron receptor -0.46
    9 GFF6590 Niacin transporter NiaP -0.45
    10 GFF7257 KEGG: LacI family transcriptional regulator, gluconate utilization system Gnt-I transcriptional repressor -0.45
    11 GFF825 no description -0.45
    12 GFF4463 alpha-methyl-L-serine aldolase -0.44
    13 GFF839 Retron-type RNA-directed DNA polymerase (EC 2.7.7.49) -0.44
    14 GFF68 UDP-glucose 4-epimerase (EC 5.1.3.2) -0.44
    15 GFF2584 Sulfate permease -0.43
    16 GFF3794 hypothetical protein -0.43
    17 GFF7270 Altronate dehydratase (EC 4.2.1.7) -0.43
    18 GFF96 RNA polymerase ECF-type sigma factor -0.43
    19 GFF6566 hypothetical protein -0.43
    20 GFF5202 hypothetical protein -0.43

    Or look for positive cofitness