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  • Negative cofitness for GFF3937 from Sphingobium sp. HT1-2

    tRNA-i(6)A37 methylthiotransferase (EC 2.8.4.3)
    SEED: tRNA-i(6)A37 methylthiotransferase
    KEGG: bifunctional enzyme involved in thiolation and methylation of tRNA

    Computing cofitness values with 18 experiments...

    Genes with the strongest negative cofitness:

    Rank Hit Name Description Cofit  
    1 GFF4294 DNA-binding protein HU-beta -0.83
    2 GFF4735 HlyD family secretion protein -0.82
    3 GFF4508 hypothetical protein -0.79
    4 GFF750 Ribosomal silencing factor RsfA -0.78
    5 GFF5352 hypothetical protein -0.77
    6 GFF1892 Nucleoside-diphosphate-sugar epimerase -0.76
    7 GFF1944 hypothetical protein -0.75
    8 GFF990 3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.157); 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) -0.74
    9 GFF4987 conserved hypothetical protein -0.73
    10 GFF2741 L-2,4-diaminobutyric acid acetyltransferase (EC 2.3.1.178) -0.73
    11 GFF2748 Pole remodelling regulatory diguanylate cyclase -0.72
    12 GFF3401 L-lactate dehydrogenase (EC 1.1.1.27) -0.72
    13 GFF4504 Chaperone protein ClpB (ATP-dependent unfoldase) -0.72
    14 GFF2297 hypothetical protein -0.70
    15 GFF3863 putative oxidoreductase, nitronate monooxygenase family -0.68
    16 GFF4935 hypothetical protein -0.68
    17 GFF3705 Flagellar hook-associated protein FlgK -0.68
    18 GFF1135 hypothetical protein -0.68
    19 GFF1324 hypothetical protein -0.67
    20 GFF3830 hypothetical protein -0.67

    Or look for positive cofitness