Negative cofitness for PS417_19350 from Pseudomonas simiae WCS417

GTP cyclohydrolase
SEED: GTP cyclohydrolase I (EC 3.5.4.16) type 1
KEGG: GTP cyclohydrolase I

Computing cofitness values with 552 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	PS417_16465		sirohydrochlorin ferrochelatase	-0.41
2	PS417_12290		sulfite reductase	-0.39
3	PS417_03925		nicotinate-nucleotide pyrophosphorylase	-0.38
4	PS417_22385		quinolinate synthase A	-0.36
5	PS417_19545		peptide synthase	-0.36
6	PS417_20125		phosphoribosylglycinamide formyltransferase	-0.36
7	PS417_27875		histidine kinase	-0.35
8	PS417_28160		hypothetical protein	-0.33
9	PS417_23110		2-isopropylmalate synthase	-0.32
10	PS417_26745		methionine biosynthesis protein MetW	-0.32
11	PS417_26740		homoserine acetyltransferase	-0.31
12	PS417_18530		O-succinylhomoserine sulfhydrylase	-0.31
13	PS417_23800		ketol-acid reductoisomerase	-0.31
14	PS417_18560		N-(5'-phosphoribosyl)anthranilate isomerase	-0.31
15	PS417_24120		integrase	-0.30
16	PS417_18595		3-isopropylmalate dehydratase	-0.30
17	PS417_18585		3-isopropylmalate dehydrogenase	-0.30
18	PS417_27040		3-phosphoglycerate dehydrogenase	-0.30
19	PS417_21750		acetyl-CoA synthetase	-0.30
20	PS417_25715		anthranilate phosphoribosyltransferase	-0.30

Or look for positive cofitness