Negative cofitness for GFF3458 from Sphingobium sp. HT1-2

3-isopropylmalate dehydrogenase (EC 1.1.1.85)
SEED: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)
KEGG: 3-isopropylmalate dehydrogenase

Computing cofitness values with 18 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	GFF967		Nucleoside-diphosphate-sugar epimerases	-0.84
2	GFF4055		ATP-dependent Clp protease ATP-binding subunit ClpX	-0.80
3	GFF2792		hypothetical protein	-0.80
4	GFF4227		dTDP-glucose 4,6-dehydratase (EC 4.2.1.46)	-0.80
5	GFF240		ABC transporter, substrate-binding protein (cluster 5, nickel/peptides/opines)	-0.78
6	GFF4438		Plasmid replication protein RepA	-0.77
7	GFF1519		Protein containing domains DUF403	-0.77
8	GFF4171		Phosphoenolpyruvate synthase regulatory protein	-0.77
9	GFF3480		ATP-dependent RNA helicase Atu1833	-0.75
10	GFF2770		hypothetical protein	-0.75
11	GFF1520		Protein containing domains DUF404, DUF407	-0.75
12	GFF1714		putative membrane protein	-0.72
13	GFF2701		Cobalt/zinc/cadmium resistance protein CzcD	-0.72
14	GFF1715		hypothetical protein	-0.72
15	GFF5247		hypothetical protein	-0.72
16	GFF2767		Transcriptional regulator, AcrR family	-0.71
17	GFF2597		Quinohemoprotein amine dehydrogenase gamma subunit (EC 1.4.99.-)	-0.70
18	GFF3819		PTS system permease (IIAMan), nitrogen regulatory IIA protein	-0.70
19	GFF3352		TonB-dependent receptor	-0.69
20	GFF3473		ATP synthase protein I	-0.69

Or look for positive cofitness