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  • Negative cofitness for PS417_16465 from Pseudomonas simiae WCS417

    sirohydrochlorin ferrochelatase
    SEED: Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)
    KEGG: uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase

    Computing cofitness values with 552 experiments...

    Genes with the strongest negative cofitness:

    Rank Hit Name Description Cofit  
    1 PS417_19350 GTP cyclohydrolase -0.41
    2 PS417_08920 branched-chain amino acid ABC transporter substrate-binding protein -0.41
    3 PS417_09620 lipopolysaccharide biosynthesis protein -0.41
    4 PS417_26125 glutathione S-transferase -0.39
    5 PS417_09585 acetyltransferase -0.39
    6 PS417_09645 TonB-dependent receptor -0.37
    7 PS417_09615 glycosyl transferase family 1 -0.37
    8 PS417_09600 glycosyl transferase family 1 -0.36
    9 PS417_09590 membrane protein -0.36
    10 PS417_04435 uracil phosphoribosyltransferase -0.35
    11 PS417_24600 hydrogenase -0.34
    12 PS417_26775 thiazole synthase -0.34
    13 PS417_09595 membrane protein -0.34
    14 PS417_02975 3-dehydroquinate dehydratase -0.33
    15 PS417_01945 nuclease -0.33
    16 PS417_09635 mannose-1-phosphate guanylyltransferase -0.32
    17 PS417_24385 tRNA (uracil-5-)-methyltransferase -0.32
    18 PS417_18475 Pyrrolidone-carboxylate peptidase -0.32
    19 PS417_05140 dipicolinate synthase -0.31
    20 PS417_21105 aminodeoxychorismate synthase -0.31

    Or look for positive cofitness