Negative cofitness for GFF3049 from Sphingobium sp. HT1-2

Transcriptional regulator, Crp/Fnr family
SEED: cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
KEGG: CRP/FNR family transcriptional regulator, anaerobic regulatory protein

Computing cofitness values with 18 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	GFF2079		Enolase (EC 4.2.1.11)	-0.77
2	GFF56		hypothetical protein	-0.77
3	GFF5150		Oxidoreductase, short-chain dehydrogenase/reductase family	-0.76
4	GFF4851		Multidomain signal transduction protein including CheB-like methylesterase, CheR-like methyltransferase and BaeS-like histidine kinase	-0.76
5	GFF3062		Imidazole glycerol phosphate synthase cyclase subunit	-0.75
6	GFF1855		Precorrin-6Y C(5,15)-methyltransferase [decarboxylating] (EC 2.1.1.132)	-0.75
7	GFF3212		Na(+)/H(+) antiporter	-0.75
8	GFF1975		Glycine/D-amino acid oxidases (deaminating)	-0.75
9	GFF1860		Precorrin-3B synthase	-0.74
10	GFF1851		Precorrin-6A synthase (deacetylating) (EC 2.1.1.152)	-0.74
11	GFF411		Uncharacterized UPF0118 membrane protein	-0.73
12	GFF4001		Phage protein	-0.73
13	GFF4968		pectin acetylesterase	-0.73
14	GFF116		Uncharacterized ABC1 family protein XCC_1720	-0.73
15	GFF1853		Precorrin-4 C(11)-methyltransferase (EC 2.1.1.133)	-0.72
16	GFF1857		Precorrin-3B C(17)-methyltransferase (EC 2.1.1.131)	-0.72
17	GFF1852		Hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolyzing) (EC 6.3.5.9)	-0.72
18	GFF356		Sulfur carrier protein ThiS / Thiazole synthase (EC 2.8.1.10)	-0.72
19	GFF1922		Glycine cleavage system H protein	-0.72
20	GFF4989		Biotin carboxylase (EC 6.3.4.14)	-0.72

Or look for positive cofitness