Negative cofitness for GFF289 from Variovorax sp. SCN45

Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
SEED: Probable HesA/MoeB/ThiF family protein

Computing cofitness values with 61 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 GFF5356 Aldose 1-epimerase -0.61
2 GFF3718 Peroxyureidoacrylate/ureidoacrylate amidohydrolase RutB (EC 3.5.1.110) -0.58
3 GFF3497 Transcriptional regulator, Crp/Fnr family -0.54
4 GFF6230 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain -0.53
5 GFF2208 Type II/IV secretion system ATP hydrolase TadA/VirB11/CpaF, TadA subfamily -0.53
6 GFF3809 Outer membrane receptor proteins, mostly Fe transport -0.52
7 GFF5711 hypothetical protein -0.52
8 GFF2672 ABC transporter, ATP-binding protein -0.52
9 GFF3662 hypothetical protein -0.52
10 GFF6139 Serine/threonine kinase -0.51
11 GFF5021 Tripartite tricarboxylate transporter TctA family -0.51
12 GFF5307 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.241) -0.50
13 GFF5009 hypothetical protein -0.50
14 GFF3441 Hypothetical protein VC0266 (sugar utilization related?) -0.50
15 GFF5920 no description -0.50
16 GFF5844 Phospholipase A1 (EC 3.1.1.32) (EC 3.1.1.4) @ Outer membrane phospholipase A -0.50
17 GFF4867 Enoyl-CoA hydratase (EC 4.2.1.17) -0.49
18 GFF2182 Inner membrane component of TAM transport system -0.49
19 GFF5377 Transcriptional regulator, AcrR family -0.49
20 GFF512 ABC transporter, ATP-binding protein 1 (cluster 4, leucine/isoleucine/valine/benzoate) -0.49

Or look for positive cofitness