Negative cofitness for GFF2576 from Variovorax sp. SCN45

6-carboxy-5,6,7,8-tetrahydropterin synthase (EC 4.1.2.50)
SEED: 6-carboxytetrahydropterin synthase (EC 4.1.2.50) @ Queuosine biosynthesis QueD, PTPS-I
KEGG: 6-pyruvoyl tetrahydrobiopterin synthase

Computing cofitness values with 61 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	GFF4530		MBL-fold metallo-hydrolase superfamily	-0.86
2	GFF2575		Quinolinate synthetase (EC 2.5.1.72)	-0.83
3	GFF2027		2-hydroxychromene-2-carboxylate isomerase family protein	-0.82
4	GFF2574		Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19)	-0.79
5	GFF937		Biotin synthase (EC 2.8.1.6)	-0.74
6	GFF305		uncharacterized domain / RidA/YER057c/UK114 superfamily, group 5	-0.71
7	GFF2356		RNase adapter protein RapZ	-0.71
8	GFF3289		Putative phosphoesterase	-0.68
9	GFF795		5-methyltetrahydropteroyltriglutamate--homocystei ne methyltransferase (EC 2.1.1.14)	-0.64
10	GFF767		Alpha-amylase (EC 3.2.1.1)	-0.63
11	GFF821		Acetoacetyl-CoA reductase (EC 1.1.1.36)	-0.62
12	GFF6022		UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9)	-0.59
13	GFF5261		Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)	-0.59
14	GFF5076		hypothetical protein	-0.59
15	GFF2579		3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11)	-0.59
16	GFF244		Cys regulon transcriptional activator CysB	-0.58
17	GFF6638		no description	-0.58
18	GFF372		PMID: 11481431	-0.56
19	GFF3838		Phosphoenolpyruvate carboxylase (EC 4.1.1.31)	-0.55
20	GFF6878		hypothetical protein	-0.55

Or look for positive cofitness