Negative cofitness for PS417_12895 from Pseudomonas simiae WCS417

pyruvate dehydrogenase
SEED: Pyruvate dehydrogenase E1 component (EC 1.2.4.1)
KEGG: pyruvate dehydrogenase E1 component

Computing cofitness values with 554 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 PS417_23730 LysR family transcriptional regulator -0.74
2 PS417_13835 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) (from data) -0.72
3 PS417_12665 hypothetical protein -0.65
4 PS417_25705 lipoate--protein ligase -0.61
5 PS417_17560 Dihydrolipoyl dehydrogenase (EC 1.8.1.4) (from data) -0.56
6 PS417_13840 isobutyryl-CoA dehydrogenase (EC 1.3.8.5) (from data) -0.56
7 PS417_27210 AsnC family transcriptional regulator -0.55
8 PS417_20580 isocitrate dehydrogenase -0.50
9 PS417_21275 GntR family transcriptional regulator -0.49
10 PS417_21065 3-methylitaconate isomerase -0.46
11 PS417_01180 ribosomal protein S6 modification protein -0.44
12 PS417_17545 2-oxoisovalerate dehydrogenase -0.40
13 PS417_10535 hypothetical protein -0.38
14 PS417_15935 Rrf2 family transcriptional regulator -0.37
15 PS417_23725 methylmalonate-semialdehyde dehydrogenase -0.37
16 PS417_17565 branched-chain amino acid aminotransferase -0.36
17 PS417_23690 Anthranilate 1,2-dioxygenase (deaminating, decarboxylating) (EC 1.14.12.1) (from data) -0.34
18 PS417_19335 isochorismatase -0.29
19 PS417_17795 ABC transporter permease -0.29
20 PS417_17550 branched-chain alpha-ketoacid dehydrogenase, E1 component beta subunit (EC 1.2.4.4) (from data) -0.28

Or look for positive cofitness