Negative cofitness for PS417_12455 from Pseudomonas simiae WCS417

hydrolase
SEED: HMP-PP hydrolase (pyridoxal phosphatase) Cof, detected in genetic screen for thiamin metabolic genes (PMID:15292217)

Computing cofitness values with 552 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	PS417_11930		hypothetical protein	-0.22
2	PS417_18605		LysR family transcriptional regulator	-0.20
3	PS417_25045		hypothetical protein	-0.19
4	PS417_05255		hypothetical protein	-0.19
5	PS417_06665		LysR family transcriptional regulator	-0.18
6	PS417_19960		membrane protein	-0.18
7	PS417_25675		membrane protein	-0.18
8	PS417_02985		diguanylate cyclase	-0.17
9	PS417_19425		allantoicase	-0.17
10	PS417_10575		DNA alkylation repair protein	-0.17
11	PS417_18435		hypothetical protein	-0.16
12	PS417_19520		transcriptional regulator	-0.16
13	PS417_06730		3-carboxy-cis,cis-muconate cycloisomerase	-0.16
14	PS417_09470		hypothetical protein	-0.16
15	PS417_13405		helicase UvrD	-0.16
16	PS417_00350		methionine ABC transporter substrate-binding protein	-0.16
17	PS417_09305		hypothetical protein	-0.16
18	PS417_16375		2-hydroxyacid dehydrogenase	-0.16
19	PS417_16520		cold-shock protein	-0.16
20	PS417_17305		hypothetical protein	-0.16

Or look for positive cofitness