Negative cofitness for GFF2383 from Variovorax sp. SCN45

Oxygen-independent coproporphyrinogen-III oxidase-like protein YggW
SEED: Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB
KEGG: oxygen-independent coproporphyrinogen III oxidase

Computing cofitness values with 61 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 GFF3582 Tripartite tricarboxylate transporter TctC family -0.79
2 GFF6424 Phosphoenolpyruvate carboxykinase [GTP] (EC 4.1.1.32) -0.77
3 GFF5307 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.241) -0.77
4 GFF6042 Fatty acid desaturase (EC 1.14.19.1); Delta-9 fatty acid desaturase (EC 1.14.19.1) -0.75
5 GFF7295 HPr kinase/phosphorylase -0.75
6 GFF2682 Protein containing domains DUF403 -0.75
7 GFF2683 Protein containing domains DUF404, DUF407 -0.75
8 GFF255 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase (EC 2.3.1.117) -0.74
9 GFF5668 Uncharacterized MFS-type transporter -0.73
10 GFF7375 Arginine:pyruvate transaminase -0.73
11 GFF5455 Pyruvate dehydrogenase E1 component (EC 1.2.4.1) -0.72
12 GFF7371 Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit A (EC 2.8.3.5) -0.70
13 GFF4397 hypothetical protein -0.70
14 GFF7373 CaiB/BaiF family protein -0.70
15 GFF3889 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) -0.69
16 GFF3923 Kynurenine formamidase, bacterial (EC 3.5.1.9) -0.68
17 GFF6200 integral membrane sensor signal transduction histidine kinase -0.68
18 GFF5325 3-dehydroquinate synthase (EC 4.2.3.4) -0.68
19 GFF7302 Glycogen synthase, ADP-glucose transglucosylase (EC 2.4.1.21) -0.68
20 GFF6230 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain -0.67

Or look for positive cofitness