Negative cofitness for GFF233 from Sphingobium sp. HT1-2

'Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) / GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II' transl_table=11
SEED: GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)
KEGG: GTP pyrophosphokinase

Computing cofitness values with 18 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 GFF1855 Precorrin-6Y C(5,15)-methyltransferase [decarboxylating] (EC 2.1.1.132) -0.95
2 GFF1859 Precorrin-8X methylmutase (EC 5.4.99.61) -0.94
3 GFF1858 Precorrin-2 C(20)-methyltransferase (EC 2.1.1.130) -0.93
4 GFF1857 Precorrin-3B C(17)-methyltransferase (EC 2.1.1.131) -0.93
5 GFF2137 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) -0.92
6 GFF1856 Precorrin-6A reductase (EC 1.3.1.54) -0.91
7 GFF1851 Precorrin-6A synthase (deacetylating) (EC 2.1.1.152) -0.91
8 GFF1852 Hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolyzing) (EC 6.3.5.9) -0.91
9 GFF1860 Precorrin-3B synthase -0.90
10 GFF1300 Phosphoglycerate mutase (EC 5.4.2.11) -0.89
11 GFF1853 Precorrin-4 C(11)-methyltransferase (EC 2.1.1.133) -0.89
12 GFF1424 Dihydroxy-acid dehydratase (EC 4.2.1.9) -0.89
13 GFF2079 Enolase (EC 4.2.1.11) -0.88
14 GFF3241 Histidinol dehydrogenase (EC 1.1.1.23) -0.88
15 GFF816 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) -0.88
16 GFF3455 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) @ O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) -0.87
17 GFF3439 Phosphoribosylformylglycinamidine synthase, PurS subunit (EC 6.3.5.3) -0.86
18 GFF2481 Prephenate dehydratase (EC 4.2.1.51) -0.86
19 GFF2054 Acetolactate synthase large subunit (EC 2.2.1.6) -0.85
20 GFF3697 Argininosuccinate synthase (EC 6.3.4.5) -0.84

Or look for positive cofitness