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  • Negative cofitness for PS417_10925 from Pseudomonas simiae WCS417

    malonate-semialdehyde dehydrogenase (acetylating) (EC 1.2.1.18) (from data)
    Original annotation: methylmalonate-semialdehyde dehydrogenase
    SEED: Methylmalonate-semialdehyde dehydrogenase [inositol] (EC 1.2.1.27)
    KEGG: methylmalonate-semialdehyde dehydrogenase

    Computing cofitness values with 552 experiments...

    Genes with the strongest negative cofitness:

    Rank Hit Name Description Cofit  
    1 PS417_22965 DNA mismatch repair protein MutT -0.50
    2 PS417_10560 choline dehydrogenase -0.45
    3 PS417_22805 hypothetical protein -0.37
    4 PS417_10565 LysR family transcriptional regulator -0.37
    5 PS417_19945 MarR family transcriptional regulator -0.32
    6 PS417_07565 hypothetical protein -0.31
    7 PS417_24680 murein transglycosylase -0.30
    8 PS417_20975 protein kinase -0.27
    9 PS417_25635 biotin--protein ligase -0.27
    10 PS417_02430 histidine kinase -0.27
    11 PS417_18355 DNA-binding protein -0.25
    12 PS417_22390 lactate dehydrogenase -0.24
    13 PS417_24220 hypothetical protein -0.22
    14 PS417_15955 secretion protein HylD -0.21
    15 PS417_05895 membrane protein -0.21
    16 PS417_01895 poly(R)-hydroxyalkanoic acid synthase -0.21
    17 PS417_08045 uracil permease -0.20
    18 PS417_09835 hypothetical protein -0.20
    19 PS417_24950 hypothetical protein -0.20
    20 PS417_20460 chromosome segregation protein SMC -0.20

    Or look for positive cofitness