Negative cofitness for GFF2027 from Variovorax sp. SCN45

2-hydroxychromene-2-carboxylate isomerase family protein
SEED: 2-hydroxychromene-2-carboxylate isomerase

Computing cofitness values with 61 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 GFF1861 Transcriptional regulator, IclR family -0.86
2 GFF6017 NADPH-dependent 7-cyano-7-deazaguanine reductase (EC 1.7.1.13) -0.83
3 GFF2576 6-carboxy-5,6,7,8-tetrahydropterin synthase (EC 4.1.2.50) -0.82
4 GFF7306 FolM Alternative dihydrofolate reductase 1 -0.81
5 GFF341 ATP-dependent Clp protease ATP-binding subunit ClpA -0.76
6 GFF5383 DNA topoisomerase III, Burkholderia type (EC 5.99.1.2) -0.74
7 GFF232 Arginine decarboxylase (EC 4.1.1.19); Ornithine decarboxylase (EC 4.1.1.17); Lysine decarboxylase (EC 4.1.1.18) -0.70
8 GFF5214 7-cyano-7-deazaguanine synthase (EC 6.3.4.20) -0.69
9 GFF2583 putative lipoprotein -0.68
10 GFF5035 Opine oxidase subunit A -0.67
11 GFF5483 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits -0.66
12 GFF3507 Transcriptional regulator, DeoR family -0.65
13 GFF5521 Ribosomal-protein-S18p-alanine acetyltransferase (EC 2.3.1.128) -0.63
14 GFF5464 Transcriptional regulator, AcrR family -0.63
15 GFF1165 2-isopropylmalate synthase (EC 2.3.3.13) -0.62
16 GFF4000 ATP-dependent DNA helicase UvrD/PcrA (EC 3.6.4.12) -0.62
17 GFF5262 Ferric iron ABC transporter, iron-binding protein -0.60
18 GFF6190 3-hydroxyisobutyrate dehydrogenase family protein -0.59
19 GFF237 ABC-type branched-chain amino acid transport systems, periplasmic component -0.59
20 GFF6884 FIG00932717: hypothetical protein -0.59

Or look for positive cofitness