Negative cofitness for GFF2023 from Variovorax sp. SCN45

Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4)
SEED: Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4)
KEGG: hydroxymethylglutaryl-CoA lyase

Computing cofitness values with 61 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 GFF6585 D-glycerate 2-kinase (EC 2.7.1.165) -0.58
2 GFF2575 Quinolinate synthetase (EC 2.5.1.72) -0.57
3 GFF6106 Dienelactone hydrolase family protein -0.57
4 GFF1055 Fumarylacetoacetate hydrolase family protein -0.57
5 GFF2560 FIG00932643: hypothetical protein -0.56
6 GFF1907 Transcriptional regulator, AraC family -0.56
7 GFF1232 Uncharacterized protein conserved in bacteria -0.55
8 GFF3970 Ring hydroxylating dioxygenase, alpha subunit (EC 1.14.12.13) -0.53
9 GFF4987 3-fumarylpyruvate hydrolase (EC 3.7.1.20) -0.53
10 GFF5456 L-threonate/D-erythronate transcriptional regulator, GntR family -0.53
11 GFF2183 Outer membrane component of TAM transport system -0.52
12 GFF5261 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) -0.52
13 GFF3923 Kynurenine formamidase, bacterial (EC 3.5.1.9) -0.52
14 GFF4153 ABC transporter, permease protein 1 (cluster 4, leucine/isoleucine/valine/benzoate) -0.51
15 GFF5325 3-dehydroquinate synthase (EC 4.2.3.4) -0.51
16 GFF6209 ABC transporter, ATP-binding protein (cluster 3, basic aa/glutamine/opines) -0.51
17 GFF462 BUG/TctC family periplasmic protein -0.50
18 GFF6002 DNA topoisomerase IB (poxvirus type) (EC 5.99.1.2) -0.50
19 GFF4986 3-hydroxybenzoate 6-monooxygenase (EC 1.14.13.24) -0.50
20 GFF4530 MBL-fold metallo-hydrolase superfamily -0.50

Or look for positive cofitness