Negative cofitness for GFF2000 from Variovorax sp. SCN45

Phosphomethylpyrimidine synthase ThiC (EC 4.1.99.17)
SEED: Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17)
KEGG: thiamine biosynthesis protein ThiC

Computing cofitness values with 61 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	GFF2201		hypothetical protein	-0.73
2	GFF5235		General secretion pathway protein D / Type II secretion outermembrane pore forming protein (PulD)	-0.72
3	GFF2593		Integral membrane protein	-0.70
4	GFF6545		Uncharacterized MFS-type transporter	-0.67
5	GFF6873		Aminotransferase, DegT/DnrJ/EryC1/StrS family	-0.64
6	GFF4117		Translation elongation factor Tu	-0.63
7	GFF5234		General secretion pathway protein E / Type II secretion cytoplasmic ATP binding protein (PulE, ATPase)	-0.62
8	GFF3456		Possible regulatory protein similar to urea ABC transporter, substrate binding protein	-0.62
9	GFF7158		Pirin	-0.62
10	GFF6230		Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain	-0.61
11	GFF5455		Pyruvate dehydrogenase E1 component (EC 1.2.4.1)	-0.61
12	GFF6067		Permease of the drug/metabolite transporter (DMT) superfamily	-0.61
13	GFF6585		D-glycerate 2-kinase (EC 2.7.1.165)	-0.60
14	GFF4375		FIG00463055: hypothetical protein	-0.59
15	GFF5402		Transcriptional regulator, IclR family	-0.59
16	GFF1319		no description	-0.59
17	GFF2649		putative autotransporter protein	-0.59
18	GFF6533		Methylphosphotriester-DNA--protein-cysteine S-methyltransferase (EC 2.1.1.n11) / DNA-3-methyladenine glycosylase II (EC 3.2.2.21)	-0.59
19	GFF2504		Cell division protein ZapD	-0.58
20	GFF4772		D-mannose isomerase (EC 5.3.1.7)	-0.57

Or look for positive cofitness