Negative cofitness for PS417_09320 from Pseudomonas simiae WCS417

diguanylate phosphodiesterase
SEED: diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s)

Computing cofitness values with 552 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	PS417_21750		acetyl-CoA synthetase	-0.27
2	PS417_16465		sirohydrochlorin ferrochelatase	-0.26
3	PS417_20125		phosphoribosylglycinamide formyltransferase	-0.25
4	PS417_04420		histidinol dehydrogenase	-0.24
5	PS417_18585		3-isopropylmalate dehydrogenase	-0.24
6	PS417_23995		preprotein translocase subunit SecG	-0.24
7	PS417_18600		isopropylmalate isomerase	-0.24
8	PS417_23810		acetolactate synthase 3 catalytic subunit	-0.24
9	PS417_12290		sulfite reductase	-0.24
10	PS417_18595		3-isopropylmalate dehydratase	-0.24
11	PS417_23800		ketol-acid reductoisomerase	-0.24
12	PS417_16570		isocitrate lyase	-0.23
13	PS417_27875		histidine kinase	-0.23
14	PS417_26040		malate synthase	-0.23
15	PS417_18560		N-(5'-phosphoribosyl)anthranilate isomerase	-0.23
16	PS417_26745		methionine biosynthesis protein MetW	-0.23
17	PS417_26890		dihydroxy-acid dehydratase	-0.23
18	PS417_23110		2-isopropylmalate synthase	-0.23
19	PS417_18530		O-succinylhomoserine sulfhydrylase	-0.22
20	PS417_02415		phosphoserine phosphatase	-0.22

Or look for positive cofitness