Negative cofitness for GFF1691 from Variovorax sp. SCN45

Two component, Sigma-54 Specific, central transcriptional regulator of acidic amino acid uptake
SEED: Two component, Sigma-54 Specific, central transcriptional regulator of acidic amino acid uptake
KEGG: two-component system, NtrC family, C4-dicarboxylate transport response regulator DctD

Computing cofitness values with 61 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	GFF2680		Protein of unknown function DUF1058	-0.62
2	GFF320		RNA polymerase ECF-type sigma factor	-0.58
3	GFF485		hypothetical protein	-0.56
4	GFF1658		Transcriptional regulator, LysR family	-0.53
5	GFF710		Ribose ABC transport system, permease protein RbsC (TC 3.A.1.2.1)	-0.52
6	GFF7096		2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase (EC 4.1.2.52)	-0.52
7	GFF2729		hypothetical protein	-0.52
8	GFF3974		Oxidoreductase, short-chain dehydrogenase/reductase family	-0.51
9	GFF3697		ATP-dependent DNA ligase (EC 6.5.1.1) LigC	-0.51
10	GFF820		Intracellular protease	-0.51
11	GFF5301		ABC transporter, ATP-binding protein (cluster 1, maltose/g3p/polyamine/iron); ABC transporter, ATP-binding protein (cluster 10, nitrate/sulfonate/bicarbonate)	-0.50
12	GFF1731		Short-chain dehydrogenase/reductase SDR?	-0.50
13	GFF5475		Uncharacterized MFS-type transporter	-0.49
14	GFF958		ElaB protein	-0.49
15	GFF2584		Sulfate permease	-0.49
16	GFF4287		Acyl-CoA dehydrogenase	-0.49
17	GFF3394		Benzoate ABC transporter, ATP-binding protein 1	-0.48
18	GFF6225		ABC transporter, substrate-binding protein (cluster 12, methionine/phosphonates)	-0.48
19	GFF2487		Two-component system sensor histidine kinase/response regulator hybrid	-0.48
20	GFF4423		Conjugative transfer protein TrbI	-0.48

Or look for positive cofitness