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  • Negative cofitness for GFF1573 from Sphingobium sp. HT1-2

    Enoyl-CoA hydratase (EC 4.2.1.17) => degradation of branched-chain amino acids and alpha-keto acids
    SEED: 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4)
    KEGG: enoyl-CoA hydratase

    Computing cofitness values with 18 experiments...

    Genes with the strongest negative cofitness:

    Rank Hit Name Description Cofit  
    1 GFF417 small multidrug resistance family (SMR) protein -0.77
    2 GFF5167 hypothetical protein -0.76
    3 GFF241 hypothetical protein -0.75
    4 GFF446 N-methylhydantoinase B (EC 3.5.2.14) -0.74
    5 GFF2288 Lipase -0.72
    6 GFF1776 hypothetical protein -0.72
    7 GFF1002 beta-galactosidase (EC 3.2.1.23) -0.70
    8 GFF5325 RNA polymerase ECF-type sigma factor -0.70
    9 GFF4416 Transcriptional regulator, ArsR family -0.69
    10 GFF790 hypothetical protein -0.69
    11 GFF1394 Enoyl-CoA hydratase (EC 4.2.1.17) / Delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase (EC 5.3.3.8) / 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) / 3-hydroxybutyryl-CoA epimerase (EC 5.1.2.3) -0.68
    12 GFF5159 IS66 Orf2 family protein -0.68
    13 GFF853 hypothetical protein -0.68
    14 GFF5364 hypothetical protein -0.68
    15 GFF1835 Transcriptional regulator, AraC family -0.68
    16 GFF18 hypothetical protein -0.67
    17 GFF2966 hypothetical protein -0.67
    18 GFF2934 hypothetical protein -0.67
    19 GFF1570 putative phospholipid N-methyltransferase -0.67
    20 GFF3559 hypothetical protein -0.67

    Or look for positive cofitness