Negative cofitness for GFF1422 from Variovorax sp. SCN45

L-lactate dehydrogenase
SEED: L-lactate dehydrogenase (EC 1.1.2.3)
KEGG: (S)-mandelate dehydrogenase

Computing cofitness values with 61 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 GFF1944 hypothetical protein -0.61
2 GFF7278 Transposase -0.60
3 GFF6822 Peptidase C14, caspase catalytic subunit p20 -0.58
4 GFF5121 Probable signal peptide protein -0.52
5 GFF6730 Branched-chain amino acid transport ATP-binding protein LivG (TC 3.A.1.4.1) -0.50
6 GFF6640 ABC transporter, ATP-binding protein (cluster 5, nickel/peptides/opines) / ABC transporter, ATP-binding protein (cluster 5, nickel/peptides/opines) -0.49
7 GFF4503 RNA polymerase sigma factor -0.49
8 GFF1594 Antitoxin DinJ (binds YafQ toxin) -0.49
9 GFF4962 Multidrug resistance transporter, Bcr/CflA family -0.49
10 GFF287 hypothetical protein -0.49
11 GFF2114 3-methylmercaptopropionyl-CoA ligase (EC 6.2.1.44) of DmdB2 type -0.49
12 GFF5144 no description -0.48
13 GFF2035 N-acyl-L-amino acid amidohydrolase (EC 3.5.1.14) -0.48
14 GFF2194 Tol-Pal system peptidoglycan-associated lipoprotein PAL -0.48
15 GFF3093 FIG138056: a glutathione-dependent thiol reductase -0.48
16 GFF1537 FIG01127817: hypothetical protein -0.47
17 GFF6411 Histidine ABC transporter, ATP-binding protein -0.47
18 GFF2693 no description -0.46
19 GFF3455 Two component response regulator associated with urea and amide use -0.46
20 GFF5017 Translation initiation factor SUI1-related protein -0.46

Or look for positive cofitness