Negative cofitness for GFF1292 from Variovorax sp. SCN45

Macrolide-specific efflux protein MacA
SEED: Macrolide-specific efflux protein MacA
KEGG: macrolide-specific efflux protein MacA

Computing cofitness values with 61 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 GFF444 Cob(I)alamin adenosyltransferase (EC 2.5.1.17) @ Cob(I)alamin adenosyltransferase (EC 2.5.1.17), clustered with cobalamin synthesis -0.65
2 GFF2013 Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4) -0.64
3 GFF6194 ABC transporter, ATP-binding protein (cluster 5, nickel/peptides/opines) -0.62
4 GFF426 Cobyric acid synthase (EC 6.3.5.10) -0.61
5 GFF440 CobN-like chelatase BtuS for metalloporphyrine salvage -0.61
6 GFF769 Conserved TM helix -0.60
7 GFF5372 Heme A synthase, cytochrome oxidase biogenesis protein Cox15-CtaA -0.60
8 GFF3150 Transcriptional regulator, AsnC family -0.59
9 GFF799 Rrf2 family transcriptional regulator, group III -0.59
10 GFF438 L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81) -0.59
11 GFF2845 5'-nucleotidase SurE (EC 3.1.3.5) -0.58
12 GFF1556 Tricarboxylate transport protein TctC -0.58
13 GFF450 Outer membrane vitamin B12 receptor BtuB -0.58
14 GFF2008 Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4) -0.58
15 GFF295 Ribonuclease G -0.57
16 GFF1003 HflC protein -0.57
17 GFF5876 Nitrogen regulation protein NtrY (EC 2.7.3.-) -0.57
18 GFF3250 Barstar, ribonuclease (Barnase) inhibitor -0.57
19 GFF982 Cell division protein ZapE -0.57
20 GFF3649 C-type cytochrome biogenesis protein ResA (thioredoxin) -0.57

Or look for positive cofitness