Negative cofitness for GFF1165 from Variovorax sp. SCN45

2-isopropylmalate synthase (EC 2.3.3.13)
SEED: 2-isopropylmalate synthase (EC 2.3.3.13)
KEGG: 2-isopropylmalate synthase

Computing cofitness values with 61 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 GFF6042 Fatty acid desaturase (EC 1.14.19.1); Delta-9 fatty acid desaturase (EC 1.14.19.1) -0.75
2 GFF5325 3-dehydroquinate synthase (EC 4.2.3.4) -0.73
3 GFF5307 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.241) -0.72
4 GFF255 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase (EC 2.3.1.117) -0.72
5 GFF305 uncharacterized domain / RidA/YER057c/UK114 superfamily, group 5 -0.70
6 GFF6638 no description -0.69
7 GFF6876 Aminotransferase, DegT/DnrJ/EryC1/StrS family -0.69
8 GFF3945 Phosphate transport regulator (distant homolog of PhoU) -0.68
9 GFF3923 Kynurenine formamidase, bacterial (EC 3.5.1.9) -0.67
10 GFF6106 Dienelactone hydrolase family protein -0.67
11 GFF3497 Transcriptional regulator, Crp/Fnr family -0.66
12 GFF4530 MBL-fold metallo-hydrolase superfamily -0.66
13 GFF6102 hypothetical protein -0.65
14 GFF3890 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) -0.64
15 GFF5410 Adenylate cyclase (EC 4.6.1.1) -0.64
16 GFF5870 hypothetical protein -0.63
17 GFF6878 hypothetical protein -0.63
18 GFF7295 HPr kinase/phosphorylase -0.63
19 GFF4599 Acyl-CoA hydrolase (EC 3.1.2.20) -0.63
20 GFF5487 Thymidine phosphorylase (EC 2.4.2.4) -0.63

Or look for positive cofitness