Negative cofitness for Echvi_3617 from Echinicola vietnamensis KMM 6221, DSM 17526

Domain of Unknown Function (DUF1080).
SEED: putative large, multifunctional secreted protein

Computing cofitness values with 221 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	Echvi_1243		glutamate synthases, NADH/NADPH, small subunit	-0.38
2	Echvi_1244		Glutamate synthase domain 2	-0.38
3	Echvi_3727		Phosphoenolpyruvate carboxylase	-0.37
4	Echvi_2293		Zn-dependent hydrolases, including glyoxylases	-0.35
5	Echvi_3285		homoserine O-acetyltransferase	-0.34
6	Echvi_3847		N-succinylglutamylphosphate reductase (EC 1.2.1.-) (from data)	-0.34
7	Echvi_3115		hypothetical protein	-0.34
8	Echvi_2283		Cystathionine beta-lyases/cystathionine gamma-synthases	-0.33
9	Echvi_3846		argininosuccinate synthase	-0.33
10	Echvi_2056		acetolactate synthase, large subunit, biosynthetic type	-0.33
11	Echvi_3639		Methionine synthase I (cobalamin-dependent), methyltransferase domain	-0.32
12	Echvi_2777		fused D-3-phosphoglycerate dehydrogenase / phosphoserine phosphatase (EC 1.1.1.95; EC 3.1.3.3) (from data)	-0.32
13	Echvi_3850		acetylglutamate kinase	-0.32
14	Echvi_2055		dihydroxy-acid dehydratase	-0.32
15	Echvi_3845		N-succinylglutamate synthase (from data)	-0.32
16	Echvi_3637		5,10-methylenetetrahydrofolate reductase, prokaryotic form	-0.32
17	Echvi_3638		5-methyltetrahydrofolate--homocysteine methyltransferase	-0.32
18	Echvi_1434		L-aminopeptidase/D-esterase	-0.32
19	Echvi_0446		hypothetical protein	-0.32
20	Echvi_2000		aspartate kinase / homoserine dehydrogenase (EC 2.7.2.4; EC 1.1.1.3) (from data)	-0.32

Or look for positive cofitness