Negative cofitness for EX28DRAFT_0004 from Enterobacter asburiae PDN3

Type IV leader peptidase family
SEED: Leader peptidase (Prepilin peptidase) (EC 3.4.23.43) / N-methyltransferase (EC 2.1.1.-)
KEGG: leader peptidase HopD

Computing cofitness values with 54 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	EX28DRAFT_0294		lysine-arginine-ornithine-binding periplasmic protein	-0.56
2	EX28DRAFT_1434		Protein of unknown function (DUF4225)	-0.54
3	EX28DRAFT_1205		Transcriptional regulators	-0.54
4	EX28DRAFT_3017		Bacterial regulatory proteins, luxR family	-0.52
5	EX28DRAFT_3011		Response regulator of citrate/malate metabolism	-0.50
6	EX28DRAFT_0568		Transcriptional regulator	-0.50
7	EX28DRAFT_2434		Protein of unknown function (DUF1471)	-0.49
8	EX28DRAFT_2834		Transcriptional regulator	-0.49
9	EX28DRAFT_0305		Isopentenyldiphosphate isomerase	-0.48
10	EX28DRAFT_3519		Predicted transcriptional regulators	-0.48
11	EX28DRAFT_3774		Arginine/lysine/ornithine decarboxylases	-0.47
12	EX28DRAFT_3645		ribosomal RNA small subunit methyltransferase A	-0.47
13	EX28DRAFT_3186		D-tagatose-bisphosphate aldolase, class II, non-catalytic subunit	-0.46
14	EX28DRAFT_1208		Predicted permease, DMT superfamily	-0.46
15	EX28DRAFT_0496		colanic acid biosynthesis glycosyl transferase WcaA	-0.46
16	EX28DRAFT_0997		L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily	-0.44
17	EX28DRAFT_2919		Chain length determinant protein	-0.44
18	EX28DRAFT_0509		Membrane protein involved in the export of O-antigen and teichoic acid	-0.44
19	EX28DRAFT_2864		(p)ppGpp synthetase, RelA/SpoT family	-0.44
20	EX28DRAFT_0575		Acetyltransferases, including N-acetylases of ribosomal proteins	-0.44

Or look for positive cofitness