Negative cofitness for ECD_04216 from Escherichia coli BL21

endonuclease R Type I restriction enzyme
SEED: Type I restriction-modification system, restriction subunit R (EC 3.1.21.3)
KEGG: type I restriction enzyme, R subunit

Computing cofitness values with 101 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	ECD_02657		23S rRNA C2498 2'-O-ribose methyltransferase, SAM-dependent	-0.64
2	ECD_01794		DUF2527 family heat-induced protein	-0.62
3	ECD_02268		long-chain fatty acid outer membrane transporter	-0.62
4	ECD_01121		spermidine/putrescine ABC transporter periplasmic binding protein	-0.62
5	ECD_00947		putative fimbrial-like adhesin protein	-0.61
6	ECD_02661		cysteine sulfinate desulfinase	-0.61
7	ECD_02578		hydrogenase maturation protein	-0.61
8	ECD_02637		DUF446 family protein	-0.61
9	ECD_03134		ssDNA-binding protein, function unknown	-0.60
10	ECD_02475		putative methyltransferase	-0.59
11	ECD_01124		spermidine/putrescine ABC transporter ATPase	-0.59
12	ECD_02472		cysteine and O-acetylserine exporter	-0.58
13	ECD_02409		dual specificity 23S rRNA m(2)A2503, tRNA m(2)A37 methyltransferase, SAM-dependent	-0.55
14	ECD_02642		L-serine dehydratase 2	-0.55
15	ECD_02992		putative (D)-galactarate transporter	-0.54
16	ECD_02188		O-succinylbenzoyl-CoA synthase	-0.54
17	ECD_02244		putative semialdehyde dehydrogenase	-0.54
18	ECD_02302		nucleoside (except guanosine) transporter	-0.54
19	ECD_r00015		23S ribosomal RNA	-0.54
20	ECD_01081		uncharacterized protein	-0.53

Or look for positive cofitness