Negative cofitness for ECD_03880 from Escherichia coli BL21

sensory histidine kinase in two-component regulatory system with ZraR
SEED: Sensor protein of zinc sigma-54-dependent two-component system
KEGG: two-component system, NtrC family, sensor histidine kinase HydH

Computing cofitness values with 101 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	ECD_03119		global DNA-binding transcriptional dual regulator	-0.44
2	ECD_03921		tRNA-dihydrouridine synthase A	-0.39
3	ECD_04102		ribosome-associated UPF0307 family protein	-0.38
4	ECD_00589		sensory histidine kinase in two-component regulatory system with CitB	-0.37
5	ECD_01565		putative arabinose efflux transporter	-0.37
6	ECD_03434		putative L-xylulose 5-phosphate 3-epimerase	-0.37
7	ECD_03898		extracellular polysaccharide production threonine-rich protein	-0.37
8	ECD_02650		D-ribose-binding periplasmic protein	-0.35
9	ECD_02544		COG1238 family inner membrane protein	-0.34
10	ECD_00809		multidrug efflux system protein	-0.33
11	ECD_01864		universal stress protein	-0.33
12	ECD_01105		respiratory NADH dehydrogenase 2/cupric reductase	-0.32
13	ECD_03765		sulfoquinovose isomerase	-0.32
14	ECD_00134		putative fimbrial-like adhesin protein	-0.32
15	ECD_00561		2,3-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex	-0.31
16	ECD_00466		allantoate amidohydrolase	-0.31
17	ECD_03005		N-acetylgalactosamine-specific enzyme IIB component of PTS	-0.31
18	ECD_00331		PsiF family protein	-0.31
19	ECD_01262		cyclic-di-GMP phosphodiesterase; csgD regulator; modulator of RNase II stability	-0.31
20	ECD_01751		scaffolding protein for murein synthesizing machinery	-0.31

Or look for positive cofitness