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  • Negative cofitness for ECD_02254 from Escherichia coli BL21

    chorismate synthase
    SEED: Chorismate synthase (EC 4.2.3.5)
    KEGG: chorismate synthase

    Computing cofitness values with 103 experiments...

    Genes with the strongest negative cofitness:

    Rank Hit Name Description Cofit  
    1 ECD_02579 hydrogenase maturation protein -0.57
    2 ECD_00142 poly(A) polymerase -0.50
    3 ECD_03235 putative DNA-binding transcriptional regulator -0.45
    4 ECD_02177 nucleoside triphosphatase -0.44
    5 ECD_02409 dual specificity 23S rRNA m(2)A2503, tRNA m(2)A37 methyltransferase, SAM-dependent -0.44
    6 ECD_04121 protein inhibitor of RNase E -0.44
    7 ECD_03289 d-gluconate inducible gluconate regulon transcriptional repressor -0.43
    8 ECD_04248 ribosomal-protein-S18-alanine N-acetyltransferase -0.43
    9 ECD_03690 hypothetical protein -0.43
    10 ECD_03922 phage shock protein G -0.43
    11 ECD_03082 N-acetylmannosamine kinase -0.43
    12 ECD_02569 hydrogenase 3 and formate hydrogenase complex, HycG subunit -0.42
    13 ECD_01062 ribosomal-protein-S5-alanine N-acetyltransferase -0.42
    14 ECD_02877 UPF0114 family putative inner membrane protein -0.42
    15 ECD_02661 cysteine sulfinate desulfinase -0.42
    16 ECD_r00015 23S ribosomal RNA -0.42
    17 ECD_02302 nucleoside (except guanosine) transporter -0.42
    18 ECD_03198 FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase) -0.42
    19 ECD_02854 hypothetical protein -0.42
    20 ECD_03341 putative oxidoreductase -0.42

    Or look for positive cofitness