Negative cofitness for DZA65_RS22135 from Dickeya dianthicola ME23

NAD-dependent DNA ligase LigB
SEED: DNA ligase (EC 6.5.1.2), LigB
KEGG: DNA ligase (NAD+)

Computing cofitness values with 77 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	DZA65_RS16390		hypothetical protein	-0.45
2	DZA65_RS09980		formate transporter FocA	-0.41
3	DZA65_RS21725		high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF	-0.40
4	DZA65_RS15235		AAA family ATPase	-0.39
5	DZA65_RS18945		glycosyl hydrolase	-0.38
6	DZA65_RS02550		ABC transporter ATP-binding protein	-0.38
7	DZA65_RS07440		IS5 family transposase	-0.37
8	DZA65_RS08700		ABC transporter permease subunit	-0.36
9	DZA65_RS20360		large-conductance mechanosensitive channel protein MscL	-0.35
10	DZA65_RS00250		ABC transporter permease subunit	-0.35
11	DZA65_RS03530		recombinase family protein	-0.34
12	DZA65_RS16455		phage tail protein	-0.34
13	DZA65_RS05725		N-acetyltransferase	-0.33
14	DZA65_RS12365		ABC transporter substrate-binding protein	-0.33
15	DZA65_RS19195		leu operon leader peptide	-0.33
16	DZA65_RS02785		DUF87 domain-containing protein	-0.33
17	DZA65_RS11215		potassium transporter Kup	-0.33
18	DZA65_RS12335		D-amino acid dehydrogenase	-0.32
19	DZA65_RS21995		universal stress protein UspA	-0.32
20	DZA65_RS13410		aliphatic sulfonate ABC transporter permease SsuC	-0.32

Or look for positive cofitness