Negative cofitness for DZA65_RS21135 from Dickeya dianthicola ME23

protoheme IX biogenesis protein HemY
SEED: Uncharacterized protein EC-HemY, likely associated with heme metabolism based on gene clustering with hemC, hemD in Proteobacteria (unrelated to HemY-type PPO in GramPositives)
KEGG: HemY protein

Computing cofitness values with 77 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 DZA65_RS21365 YifB family Mg chelatase-like AAA ATPase -0.50
2 DZA65_RS21660 sn-glycerol-3-phosphate ABC transporter permease UgpA -0.48
3 DZA65_RS04815 hypothetical protein -0.46
4 DZA65_RS14400 type IV secretion system protein -0.46
5 DZA65_RS17740 murein L,D-transpeptidase -0.46
6 DZA65_RS09740 alpha/beta hydrolase -0.45
7 DZA65_RS17050 family 78 glycoside hydrolase catalytic domain -0.44
8 DZA65_RS07435 As(III)-sensing metalloregulatory transcriptional repressor ArsR -0.44
9 DZA65_RS19900 LysR family transcriptional regulator -0.44
10 DZA65_RS05710 SpoIIE family protein phosphatase -0.43
11 DZA65_RS14575 nuclear transport factor 2 family protein -0.43
12 DZA65_RS06395 galactose/methyl galactoside ABC transporter ATP-binding protein MglA -0.43
13 DZA65_RS13585 beta-N-acetylhexosaminidase -0.43
14 DZA65_RS11060 rhamnogalacturonate lyase -0.42
15 DZA65_RS14170 4'-phosphopantetheinyl transferase superfamily protein -0.42
16 DZA65_RS00650 hypothetical protein -0.42
17 DZA65_RS02210 amino acid transporter -0.42
18 DZA65_RS21665 sn-glycerol-3-phosphate ABC transporter substrate-binding protein UgpB -0.42
19 DZA65_RS11495 AvrE-family type 3 secretion system effector -0.41
20 DZA65_RS11180 RES family NAD+ phosphorylase -0.41

Or look for positive cofitness