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  • Negative cofitness for Atu4157 from Agrobacterium fabrum C58

    bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase
    SEED: Proline dehydrogenase (EC 1.5.99.8) (Proline oxidase) / Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.2.1.88)
    KEGG: proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase

    Computing cofitness values with 1014 experiments...

    Genes with the strongest negative cofitness:

    Rank Hit Name Description Cofit  
    1 Atu6167 component of type IV secretion system -0.35
    2 Atu6168 component of type IV secretion system, pilin subunit -0.32
    3 Atu6170 component of type IV secretion system -0.30
    4 Atu4674 GntR family transcriptional regulator -0.28
    5 Atu2209 pyrroline-5-carboxylate reductase -0.27
    6 Atu6169 component of type IV secretion system -0.26
    7 Atu3794 FadR family transcriptional regulator -0.26
    8 Atu6175 component of type IV secretion system -0.25
    9 Atu3783 glutamate synthase subunit beta -0.25
    10 Atu3784 glutamate synthase large subunit -0.24
    11 Atu3791 L-asparaginase -0.24
    12 Atu6174 component of type IV secretion system -0.23
    13 Atu3482 pantoate--beta-alanine ligase -0.23
    14 Atu6164 trans-zeatin secretion protein -0.22
    15 Atu2747 hypothetical protein -0.22
    16 Atu3289 thiamine-phosphate pyrophosphorylase -0.22
    17 Atu3483 3-methyl-2-oxobutanoate hydroxymethyltransferase -0.22
    18 Atu3495 diguanylate cyclase -0.22
    19 Atu0944 sucrose hydrolase -0.22
    20 Atu1334 aspartate transaminase -0.22

    Or look for positive cofitness