Negative cofitness for Atu3899 from Agrobacterium fabrum C58

siroheme synthase
SEED: Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)
KEGG: uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase

Computing cofitness values with 1014 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 Atu2399 hypothetical protein -0.23
2 Atu3658 MerR family transcriptional regulator -0.23
3 Atu2464 formyltetrahydrofolate deformylase -0.22
4 Atu0368 tRNA pseudouridine synthase I -0.22
5 Atu3635 amidohydrolase -0.20
6 Atu3636 hypothetical protein -0.20
7 Atu3644 hypothetical protein -0.20
8 Atu0469 hypothetical protein -0.19
9 Atu8024 hypothetical protein -0.19
10 Atu4671 response regulator -0.19
11 Atu0470 hypothetical protein -0.19
12 Atu2064 hypothetical protein -0.18
13 Atu0692 glutathione-regulated potassium-efflux system protein -0.18
14 Atu1993 tRNA/rRNA metyltransferase -0.18
15 Atu3537 hypothetical protein -0.18
16 Atu3822 hypothetical protein -0.18
17 Atu3620 hypothetical protein -0.18
18 Atu1368 hypothetical protein -0.18
19 Atu0893 ABC transporter, nucleotide binding/ATPase protein -0.18
20 Atu3662 hypothetical protein -0.17

Or look for positive cofitness