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  • Negative cofitness for Atu3480 from Agrobacterium fabrum C58

    hydroxymethylglutaryl-CoA lyase
    SEED: Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4)
    KEGG: hydroxymethylglutaryl-CoA lyase

    Computing cofitness values with 1014 experiments...

    Genes with the strongest negative cofitness:

    Rank Hit Name Description Cofit  
    1 Atu2376 hypothetical protein -0.39
    2 Atu0099 prephenate dehydratase -0.35
    3 Atu0332 RNA polymerase sigma-54 factor -0.34
    4 Atu2709 3-isopropylmalate dehydratase, large subunit -0.34
    5 Atu2264 2-isopropylmalate synthase -0.34
    6 Atu0679 ATP phosphoribosyltransferase -0.33
    7 Atu2718 homoserine O-succinyltransferase -0.33
    8 Atu2791 3-isopropylmalate dehydrogenase -0.33
    9 Atu0678 histidyl-tRNA synthetase -0.33
    10 Atu0537 histidinol dehydrogenase -0.32
    11 Atu1750 phosphoribosyl c-AMP cyclohydrolase -0.32
    12 Atu3706 D-3-phosphoglycerate dehydrogenase -0.32
    13 Atu2790 3-isopropylmalate dehydratase, small subunit -0.32
    14 Atu2155 methionine synthase -0.31
    15 Atu3885 inositol monophosphatase -0.31
    16 Atu3707 phosphoserine aminotransferase -0.31
    17 Atu0432 O-succinylhomoserine sulfhydrylase -0.31
    18 Atu2289 anthranilate synthase component I and II -0.30
    19 Atu1205 threonine dehydratase -0.29
    20 Atu0035 phosphoenolpyruvate carboxykinase -0.29

    Or look for positive cofitness