Negative cofitness for Atu3473 from Agrobacterium fabrum C58

2-oxoisovalerate dehydrogenase subunit alpha
SEED: Branched-chain alpha-keto acid dehydrogenase, E1 component, alpha subunit (EC 1.2.4.4)
KEGG: 2-oxoisovalerate dehydrogenase E1 component, alpha subunit

Computing cofitness values with 1003 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	Atu2718		homoserine O-succinyltransferase	-0.28
2	Atu2791		3-isopropylmalate dehydrogenase	-0.28
3	Atu2264		2-isopropylmalate synthase	-0.27
4	Atu2709		3-isopropylmalate dehydratase, large subunit	-0.27
5	Atu0099		prephenate dehydratase	-0.27
6	Atu8112		hypothetical protein	-0.27
7	Atu2790		3-isopropylmalate dehydratase, small subunit	-0.26
8	Atu0432		O-succinylhomoserine sulfhydrylase	-0.26
9	Atu3707		phosphoserine aminotransferase	-0.26
10	Atu0679		ATP phosphoribosyltransferase	-0.25
11	Atu0041		glutamine amidotransferase	-0.25
12	Atu1205		threonine dehydratase	-0.25
13	Atu0678		histidyl-tRNA synthetase	-0.25
14	Atu1750		phosphoribosyl c-AMP cyclohydrolase	-0.24
15	Atu3706		D-3-phosphoglycerate dehydrogenase	-0.24
16	Atu0537		histidinol dehydrogenase	-0.24
17	Atu1334		aspartate transaminase	-0.23
18	Atu4472		hypothetical protein	-0.23
19	Atu2376		hypothetical protein	-0.23
20	Atu2124		transcriptional regulator, ArsR family	-0.23

Or look for positive cofitness