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  • Negative cofitness for Atu1815 from Agrobacterium fabrum C58

    HlyD family secretion protein
    SEED: Macrolide-specific efflux protein MacA
    KEGG: HlyD family secretion protein

    Computing cofitness values with 1014 experiments...

    Genes with the strongest negative cofitness:

    Rank Hit Name Description Cofit  
    1 Atu3683 peptide synthetase, siderophore biosynthesis protein -0.41
    2 Atu3675 peptide synthetase, siderophore biosynthesis protein -0.39
    3 Atu3670 siderophore biosynthesis protein -0.38
    4 Atu3682 non-ribosomal peptide synthetase, siderophore biosynthesis protein -0.38
    5 Atu3671 siderophore biosynthesis protein -0.38
    6 Atu3681 polyketide synthase -0.36
    7 Atu3672 polyketide synthase -0.35
    8 Atu3673 siderophore biosynthesis protein -0.34
    9 Atu0399 dihydroorotase -0.33
    10 Atu2650 glycerol-3-phosphate dehydrogenase -0.33
    11 Atu0017 N-(5-phosphoribosyl) anthranilate isomerase -0.33
    12 Atu2289 anthranilate synthase component I and II -0.33
    13 Atu0486 dihydroorotate dehydrogenase -0.33
    14 Atu1687 anthranilate phosphoribosyltransferase -0.33
    15 Atu0400 orotate phosphoribosyltransferase -0.33
    16 Atu1688 indole-3-glycerol-phosphate synthase -0.33
    17 Atu0298 orotidine 5 -0.32
    18 Atu1308 aspartate carbamoyl transferase catalytic subunit -0.32
    19 Atu3676 siderophore biosynthesis protein -0.32
    20 Atu2791 3-isopropylmalate dehydrogenase -0.32

    Or look for positive cofitness