Negative cofitness for b3475 from Escherichia coli BW25113

acpT: holo-(acyl carrier protein) synthase 2 (NCBI)
SEED: 4'-phosphopantetheinyl transferase (EC 2.7.8.-)
KEGG: 4'-phosphopantetheinyl transferase

Computing cofitness values with 1335 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 b2260 menE O-succinylbenzoic acid--CoA ligase (NCBI) -0.26
2 b2358 oweS CPS-53 (KpLE1) prophage; predicted defective phage replication protein O (RefSeq) -0.22
3 b3965 trmA tRNA (uracil-5-)-methyltransferase (NCBI) -0.21
4 b3136 agaS tagatose-6-phosphate ketose/aldose isomerase (NCBI) -0.20
5 b3289 rsmB 16S rRNA m5C967 methyltransferase, S-adenosyl-L-methionine-dependent (NCBI) -0.20
6 b1869 yecN orf, hypothetical protein (VIMSS) -0.20
7 b0119 yacL orf, hypothetical protein (VIMSS) -0.19
8 b2261 menC O-succinylbenzoate synthase (NCBI) -0.19
9 b3673 emrD 2-module integral membrane pump; multidrug resistance (VIMSS) -0.18
10 b4697 yrdF no description -0.18
11 b0195 yaeB hypothetical protein (NCBI) -0.18
12 b2298 yfcC putative S-transferase (VIMSS) -0.18
13 b3744 asnA asparagine synthetase AsnA (NCBI) -0.17
14 b0947 ycbX predicted 2Fe-2S cluster-containing protein (NCBI) -0.17
15 b2409 yfeR predicted DNA-binding transcriptional regulator (NCBI) -0.17
16 b4336 yjiN conserved inner membrane protein (NCBI) -0.17
17 b4625 ryjC Novel sRNA, function unknown (RefSeq) -0.17
18 b1304 pspA regulatory protein for phage-shock-protein operon (NCBI) -0.17
19 b2432 yfeY hypothetical protein (NCBI) -0.16
20 b2318 truA tRNA pseudouridine synthase A (NCBI) -0.16

Or look for positive cofitness