Negative cofitness for b2541 from Escherichia coli BW25113

hcaB: 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase (NCBI)
SEED: 2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase (EC 1.3.1.-)
KEGG: 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase

Computing cofitness values with 1335 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	b1590	ynfH	oxidoreductase, membrane subunit (NCBI)	-0.15
2	b0850	ybjC	predicted inner membrane protein (NCBI)	-0.15
3	b1572	ydfB	orf, hypothetical protein (VIMSS)	-0.14
4	b4357	yjjM	predicted DNA-binding transcriptional regulator (NCBI)	-0.13
5	b3878	yihQ	alpha-glucosidase (NCBI)	-0.13
6	b2129	yehX	predicted transporter subunit: ATP-binding component of ABC superfamily (NCBI)	-0.13
7	b2128	yehW	predicted transporter subunit: membrane component of ABC superfamily (NCBI)	-0.12
8	b2399	yfeD	predicted DNA-binding transcriptional regulator (RefSeq)	-0.12
9	b1442	ydcU	predicted spermidine/putrescine transporter subunit (NCBI)	-0.12
10	b3618	htrL	involved in lipopolysaccharide biosynthesis (VIMSS)	-0.12
11	b1787	yeaK	hypothetical protein (NCBI)	-0.12
12	b1386	tynA	tyramine oxidase, copper-requiring (NCBI)	-0.12
13	b2248	yfaX	predicted DNA-binding transcriptional regulator (NCBI)	-0.11
14	b4315	fimI	fimbrial protein (VIMSS)	-0.11
15	b4472	yhdP	conserved membrane protein, predicted transporter (NCBI)	-0.11
16	b2214	yojL	predicted thiamine biosynthesis lipoprotein (NCBI)	-0.11
17	b2637	yfjT	CP4-57 prophage; predicted protein (NCBI)	-0.11
18	b0599	ybdH	predicted oxidoreductase (NCBI)	-0.11
19	b2449	yffR	CPZ-55 prophage; predicted protein (NCBI)	-0.11
20	b3897	frvR	predicted regulator (NCBI)	-0.11

Or look for positive cofitness